Uncertainty exists regarding whether or not intermittent fasting diets improve the clinical markers of glycolipid metabolism. In order to assess the effects of intermittent fasting on lipid and glucose metabolism as well as insulin sensitivity in individuals with metabolic syndrome, this study thoroughly examined the pertinent clinical trials. Random-effect or fixedeffect meta-analysis models were used to determine the average difference between before and after intermittent fasting diet intervention and the corresponding 95% confidence intervals in order to assess the impact of intermittent fasting diet intervention on patients with disorders of glucose and lipid metabolism (CIs). The clinical indicators of glycolipid metabolism may or may not be improved by intermittent fasting diets.