Atherosclerosis is the common cardiac disease engaging heart and brain. This condition progresses slowly from childhood and gets manifested completely into adulthood. It is found that the progression of atherosclerosis is related to other factors. They include the risk factors of coronary artery disease, hypercholesterolemia, smoking, oxidative stress associated with free radicals in the blood, diabetes, age, hypertension, inflammatory factors, hyperhomocysteinemia, male gender, history of cardiac ischemia in the family, enhanced lipoprotein A, obesity, physical inactivity, alcohol, increased blood clotting, and psychiatric factors. Recent studies show that plant-based compounds can aid in the treatment and prevention of atherosclerosis by influencing the factors associated with it. It has been found that the antioxidant properties of certain medicinal plants are effective on lipids and in reducing plaque development, atherosclerosis progression, cardiovascular disease development and ischemia. Antioxidants, phenols, and flavonoids are the plant-based compounds that are effective in reducing atherosclerosis predisposing factors, in preventing complications of the disease, in reducing cholesterol, in preventing the increase of free radicals, in reducing vascular plaque and vascular resistance. The medicinal plants, whose extracts are studied to be beneficial in clearing the plaques of atherosclerotic effect include Quercus, Medicago sativa Linn, Gundelia tournefortii, Pulicaria gnaphalodes, Valeriana officinalis, Eremurus persicus, Sesamum indicum Linn, Allium ampeloprasum, Allium latifolium, Origanum majorana sps., Morus nigra fruit, Linum usitatissimum, Portulaca oleracea Linn, Silybum marianum Linn, and so on.

International Journal of Collaborative Research on Internal Medicine and Public health broadcasts peer-reviewed content covering wide range of non-surgical clinical aspects which includes disease prognosis, pathological manifestations and medical counselling. The journal lays special emphasizes on contributions that address the emerging challenges in the diagnosis and clinical investigation of complex and important diseases in adults that necessitate cross-specialization approach. IJCRIMPH has the goal to become the place where outstanding clinical studies can be published; furthermore, this purpose is intended to be synonymous with improving the quality of healthcare in internal medicine.

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