Human immunological disorder virus infected people square measure vulnerable to deficiency disease thanks to increased energy necessities, disease and increased destructive metabolism. Trace parts like Zn and antioxidant have major role in maintaining a healthy system. This study was designed to guage the organic process standing of Iranian subjects United Nations agency were freshly diagnosed with human immunological disorder viral infection and to match bodily fluid level of zinc and selenium in these patients with those of the sex and aged match healthy subjects.