Abstract

Adult sepsis is characterised by life-threatening organ failure brought on by a dysregulated host response to infection, according to the Sepsis-3 agreement [3]. The International Pediatric Sepsis Definition Taskforce is developing a definition for paediatric sepsis and has identified robust correlations between organ dysfunction indicators and clinical outcomes that are appropriate for inclusion in the validation stage of the definition [4]. Neonatal sepsis standards, however, differ from those for adults and kids because many doctors still prioritise microbiological findings above organ failure [5]. In addition to the absence of a long-term outcome or core outcome dataset to standardise clinical studies of sepsis and enable comparison between trials, there is also a lack of a globally agreed-upon consensus definition of neonatal sepsis. The Surviving Sepsis Campaign's recommendations emphasised the importance of conducting clinical studies to investigate paediatric sepsis identification and QI screening tool algorithms to identify clinical worsening [6]. The electronic health record has played a key role in the recent rapid development of sepsis detection systems. Eisenberg et al. outline the many sepsis screening methods that have developed and talk about the possibility of alarm fatigue if a large number of false positives are found [7].