Reaction of pain

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This is a long pathway, in which neurons make connections in both the brain and the spinal cord. Explain what happens when one slams a door on one's finger. First, nerve endings in the finger sense the injury to the finger (sensory neurons) and they send impulses along axons to the spinal cord (magenta pathway). The incoming axons form a synapse with neurons that project up to the brain. The neurons that travel up the spinal cord then form synapses with neurons in the thalamus, which is a part of the midbrain (magenta circle). The thalamus organizes this information and sends it to the sensory cortex (blue), which interprets the information as pain and directs the nearby motor cortex (orange) to send information back to the thalamus (green pathway).